Association between blood pressure levels over time and brain atrophy in the elderly.
作者： Tom den Heijer , Ingmar Skoog , Matthijs Oudkerk , Frank-Erik de Leeuw , Jan Cees de Groot
DOI: 10.1016/S0197-4580(02)00088-X
关键词:
摘要: The relation between blood pressure level and degree of global brain atrophy is equivocal. We evaluated past present levels change in over 20 years to the cortical on magnetic resonance imaging (MRI). In 1995-1996, we measured performed MRI 1077 nondemented elderly (age 60-90 years). For 513 these, had information a before. was semi-quantitatively scored (range 0-15). late life, high (>/=90 mmHg) low (<65 diastolic were associated with more than 65-74 mmHg (adjusted difference 0.60 units (95% confidence interval (CI), 0.18-1.02) 0.77 (0.28-1.25), respectively). Persons whose declined 10 those stable 0.53 units, 0.05-1.02). Both declining are MRI.
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