The C‐terminal cysteine of turbot Scophthalmus maximus translationally controlled tumour protein plays a key role in antioxidation and growth‐promoting functions
作者： Z.-X. Zhang , D.-Y. Geng , Q. Han , S.-D. Liang , H.-R. Guo
DOI: 10.1111/JFB.12231
关键词:
摘要: The translationally controlled tumour protein (TCTP) of turbot Scophthalmus maximus (SmTCTP) contains only one cysteine (Cys¹⁷⁰) at the C-terminal end. biological role this Cys¹⁷⁰ in antioxidation and growth-promoting functions SmTCTP was examined by site-directed mutation C170A (Cys¹⁷⁰ →Ala¹⁷⁰). It found that not obviously decreased capacity mutant-smtctp-transformed bacteria exposed to 0·22 mM hydrogen peroxide, but also significantly interrupted normal growth survival flounder Paralichthys olivaceus gill (FG) cells, indicating a key played SmTCTP. This study suggested self-dimerization or dimerization with other interacting proteins is critical function
sci-hub.se 参考文章(43)
Roy Bheekha-Escura, Donald W. MacGlashan, Jacqueline M. Langdon, Susan M. MacDonald, Human recombinant histamine-releasing factor activates human eosinophils and the eosinophilic cell line, AML14-3D10 Blood. ,vol. 96, pp. 2191- 2198 ,(2000) , 10.1182/BLOOD.V96.6.2191.H8002191_2191_2198
Gaestel M, Gross B, Böhm H, Bielka H, Benndorf R, Nürnberg P, Otto A, Kraft R, The growth-related protein P23 of the Ehrlich ascites tumor: translational control, cloning and primary structure. Biochemistry international. ,vol. 19, pp. 277- 286 ,(1989)
Paul Thaw, Nicola J. Baxter, Andrea M. Hounslow, Clive Price, Jonathan P. Waltho, C. Jeremy Craven, Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones Nature Structural & Molecular Biology. ,vol. 8, pp. 701- 704 ,(2001) , 10.1038/90415
Holger Thiele, Mario Berger, Angela Skalweit, Bernd-Joachim Thiele, Expression of the gene and processed pseudogenes encoding the human and rabbit translationally controlled tumour protein (TCTP). FEBS Journal. ,vol. 267, pp. 5473- 5481 ,(2000) , 10.1046/J.1432-1327.2000.01609.X
Hyung Sik Kang, Min Ju Lee, Hyunkeun Song, Seung Hyun Han, Yong Man Kim, Joo Young Im, Inpyo Choi, Molecular Identification of IgE-Dependent Histamine-Releasing Factor as a B Cell Growth Factor The Journal of Immunology. ,vol. 166, pp. 6545- 6554 ,(2001) , 10.4049/JIMMUNOL.166.11.6545
Christine Bonnet, Eric Perret, Xavier Dumont, Anr� Picard, Daniel Caput, Guy Lenaers, Identification and transcription control of fission yeast genes repressed by an ammonium starvation growth arrest. Yeast. ,vol. 16, pp. 23- 33 ,(2000) , 10.1002/(SICI)1097-0061(20000115)16:1<23::AID-YEA503>3.0.CO;2-A
Aimin XU, A. Richard BELLAMY, John A. TAYLOR, Expression of translationally controlled tumour protein is regulated by calcium at both the transcriptional and post-transcriptional level. Biochemical Journal. ,vol. 342, pp. 683- 689 ,(1999) , 10.1042/0264-6021:3420683
Hans Böhm, Heinz Bielka, Burck Gross, Matthias Gaestel, cDNA sequence coding for a translationally controlled human tumor protein Nucleic Acids Research. ,vol. 17, pp. 8367- 8367 ,(1989) , 10.1093/NAR/17.20.8367
S.R. Stürzenbaum, P. Kille, A.J. Morgan, Identification of heavy metal induced changes in the expression patterns of the translationally controlled tumour protein (TCTP) in the earthworm Lumbricus rubellus Biochimica et Biophysica Acta. ,vol. 1398, pp. 294- 304 ,(1998) , 10.1016/S0167-4781(98)00077-3
Gnanasekar Munirathinam, Kalyanasundaram Ramaswamy, Sumoylation of Human Translationally Controlled Tumor Protein Is Important for Its Nuclear Transport Biochemistry Research International. ,vol. 2012, pp. 831940- 831940 ,(2012) , 10.1155/2012/831940