Evidence for polymorphonuclear leukocyte collagenase and 92-kilodalton gelatinase in gingival crevicular fluid.

作者: C M Overall , J Sodek , C A McCulloch , P Birek

DOI: 10.1128/IAI.59.12.4687-4692.1991

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摘要: Abstract Analysis of inflammatory exudate collected from sites experimental periodontitis in cynomolgus monkeys has revealed the presence collagenase and a 92-kDa gelatinase that comigrated after electrophoresis with released polymorphonuclear leukocytes. Since neutralizing antibodies to fibroblast had no effect on activity bacterial collagenases could not be detected, leukocytes appear major source collagenolytic proteinases fluid gingiva.

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