Perioperative Prophylaxis for Total Artificial Heart Transplantation.

摘要: Abstract Background Practice variation regarding perioperative antimicrobial prophylaxis in total artificial heart transplantations (TAH-t) across institutions is unknown. The aim of our survey was to assess the current practices for prevention infection TAH-t recipients among different programs. Methods An electronic sent programs that implant Syncardia TAH (Syncardia Systems, Tuscon, Ariz, USA). Proportions were analyzed categorical variables; means and SDs continuous variables. Results majority centers (80.8%) had a formal surgical protocol. For non–penicillin-allergic patients, five (20.1%) reported using 4-drug regimen, seven (29.2%) used 3-drug 2-drug cephalosporin alone. Similar data seen penicillin-allergic patients. Infections occur postoperatively 52.2% centers. During first month after TAH-t, bacteremia represented 27.3%, driveline infections 27.2%, pulmonary 9%, mediastinal 18.2%. most common organisms within Candida spp., Escherichia coli, Pseudomonas aeruginosa (21.4%). In 65% centers, mean rate death post–TAH-t due 14.5% (SD, 22.3%). patients surviving until orthotopic transplantation 58.6% 27.7%). Conclusions Preventing key decreasing morbidity mortality. All administered with significant have prophylactic