摘要: Hypertension is a major risk factor for cardiovascular disease. Early diagnosis and timely intervention in disease progression lead to better outcomes reduced risk. Plasma biomarkers predictive of blood pressure elevation may shed light on the underlying molecular processes contributing hypertension could facilitate prediction developing hypertension. Accordingly, discovery reliable informative markers predict track therapeutic efficacy becoming increasingly important. Numerous have been identified, however, most still require validation. Discussed this chapter are endothelial dysfunction, an important early event development