The reaction of aralkyl sulphate esters with glutathione catalysed by rat liver preparations.

作者: B. Gillham

DOI: 10.1042/BJ1210667

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摘要: 1. Rat liver supernatant preparations catalyse the reactions of some aralkyl sulphate esters with GSH to yield S-aralkylglutathione derivatives. 2. A glutathione S-transferase that catalyses these has been purified 16-fold. 3. The enzyme preparation release ions from benzyl sulphate, 1-menaphthyl (naphth-1-ylmethyl) and phenanthr-9-ylmethyl only in presence GSH. It does not cause prop-1-yl l-serine O-sulphate, phenyl or oestrone 3-sulphate even when is added. 4. stability specificity its response inhibitors changes pH were studied. 5. activity was compared activities S-transferases described previously.

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