Incidence of Methicillin-Resistant Staphylococcus aureus (MRSA) in Microbial Community of Cancer Patients and Evaluation of Their Resistant Pattern

摘要: Cancer patients are prone to MRSA infection due a number of factors including prolonged hospitalization, intravascular catheterization, compromised host immunity, malignancy, chemotherapy, radiotherapy surgery, prior antibiotic therapy and operative time. Among 468 Staphylococcus isolates, 283 were methicillin-resistant aureus isolates (MRSA), which indicated the occurrence prevalence among cancer patients. The highest strains was isolated from male (124 isolates), female (90 isolates) followed by children (69 represent 43.82, 31.80 24.38%, respectively, all isolates. All S. exhibited resistance higher antibiotics in common use. oxacillin, cefoxitin (with MIC 256 $${>}1024\,\upmu \,\hbox {g/mL}$$ ), clindamycin, penicillin, ceftriaxone, cephalothin cefazolin ranging between 128 ) resistant. 87.63% showed various multidrug-resistant profiles (MDRPs) toward more than one drug, according their MDRPs panel 17 antibiotics, divided into seven patterns profiles. existence mecA gene corresponds 100% with methicillin phenotypic plasmid DNA profile 85 (MRSA) that 42 (49.41%) had bands.