Changes of Myocardial Structure with Aging

摘要: The functional capacity of the heart declines with advancing age (Gerstenblith et al. 1976; Lakatta 1979; und Yin 1982). diminished cardiac adaptability to stress in senescence could provide an explanation why insufficiency and death occur older people even upon only a minor increase demand (Wei Gersh 1987). Most morphological studies hearts old therefore have aim finding structural correlate for reduced age. A whole range findings on elderly humans been compiled (Pomerance 1968; Linzbach 1972): In autopsy studies, increasing degree coronary atherosclerosis was found (Linzbach 1972) as well increased fibrosis small intramural vessels (Rahlf 1980). Typical age-related changes valves are calcification mitral valve ring aortic 1967,1970; Pomerance 1978; Waller Roberts 1983). Mitral prolapse mucoid degeneration further alterations which observed more frequently senescent 1969).