作者: I. S. WECHSLER
DOI: 10.1001/ARCHNEURPSYC.1929.02210200055006
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摘要: The diagnosis of amyotrophic lateral sclerosis is usually one the easiest to make, characterized as syndrome by involvement anterior horn or nuclear cell groups, that is, lower motor neuron, and pyramidal tract, upper neuron. Generally, atrophy begins in hands and, after a variable period, degenerative process ascends involves bulbar nuclei. At some time course disease, signs tract appear. latter are most evident extremities, though hyperreflexia also points their presence region atrophies. Most often, precedes dominates picture. Rarely, appear first those referable neurons play secondary role. Sensory disturbances, however, either absent occur rarely. While subjective such mild