The effect of extracorporeal membrane oxygenation on the survival of neonates with high-risk congenital diaphragmatic hernia: 45 cases from a single institution.

摘要: At The Children's Hospital, Boston (TCH), in the 3 years before extracorporeal membrane oxygenation (ECMO) was available, infants with high-risk congenital diaphragmatic hernia (CDH) had a 47% survival rate. In February 1984, ECMO introduced and offered to all CDH 100% predicted mortality. Since 45 presented TCH. Twenty-six (58%) were supported ECMO; 19 (42%) never met criteria for mortality conventional mechanical ventilation (CMV). Overall 49%. Nine (35%) of 26 patients survived. Thirteen (68%) CMV Although there no change survival, cause death. Deaths group either early (n = 8, secondary complication or lack pulmonary improvement) late 9). deaths who successfully weaned from ECMO, CMV, died complications chronic lung disease.