The endoplasmic reticulum: a sensor of cellular stress that modulates immune responses.

作者: Fabio Martinon

DOI: 10.1016/J.MICINF.2012.07.005

关键词:

摘要: Many inflammatory and infectious diseases are characterized by the activation of signaling pathways steaming from endoplasmic reticulum (ER). These pathways, primarily associated with loss ER homeostasis, emerging as key regulators inflammation infection. Recent advances shed light on mechanisms linking ER-stress immune responses.

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