Aqueous soluble gold nanoparticle synthesis using polyethyleneimine and reduced glutathione
作者： Francois Taute , Martin Onani , Abram Madiehe , Mervin Meyer , None
DOI: 10.3139/146.111114
关键词:
摘要: Abstract Gold nanoparticles (AuNPs) are considered to be ideal drug delivery vehicles for chemotherapeutic molecules due the bio-inert nature of colloids. Critical factors which determine cellular internalization and intracellular localization AuNPs nanoparticle size as well surface charge. Polydisperse with a cationic charge, rich in primary amines would present multiple covalent molecule attachment loci chemotherapeutics have sites action. In an adapted synthesis method, polydisperse were produced soluble aqueous solution showed high chemical stability. The was conducted comparative manner using polyethyleneimine (PEI) reduced glutathione (GSH) AuNP passivation ligands. Anisotropic spherical morphologies observed PEI passivated AuNPs, where morphology dependent on ratio reducing agent Au3+ sol...
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