摘要: This chapter discusses growth hormone (GH), also known as somatotropin, which is a molecule with diverse action due in part to the widespread distribution of its receptor. GH non-glycoslated polypeptide composed 191 amino acids and can stimulate differentiation muscle, bone cartilage. In addition pituitary gland, produced many other tissues. suggests that function classic endocrine hormone, may an autocrine/ paracrine fashion. direct receptor-mediated activity, stimulates production insulin-like factors (IGFs) mediate promoting actions hormone. The structure receptors have been intensely studied chapter. These studies contributed greatly understanding receptor activation signaling.
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