Nutritional factors in epidemic Kaposi's sarcoma.

摘要: The role of nutritional factors in the management acquired immunodeficiency syndrome-related, or epidemic, Kaposi's sarcoma (EKS) is complex, since there are known interactions between malnutrition, immunodeficiency, and cancer. Malnutrition a well-established cause immune aberrations, which seen deficiencies both protein energy, as well specific nutrients, particularly trace metals. Conversely, malnutrition common result cancer immunodeficiency. Cancer patients without an obviously immunological pathogenesis frequently have cachexia, mainly decreased dietary intake poorly defined host-tumor (commonly labeled "hypermetabolic"). Patients with primary syndromes similarly experience triad diarrhea, malabsorption, weight loss, responsible for development malnutrition. This AIDS, presence sarcoma. mechanisms these EKS largely unexplored; although some can be explained by enteropathic effects opportunistic infections, others not. Some investigators advocated careful evaluation all AIDS patients, vigorous support to provided where assessment reveals suboptimal status. Specific nutrient been reported, selenium may most interesting; preliminary data indicate that it malnutrition-related immunodepression AIDS. Such supportive measures significantly improve symptomatic relief, but yet no evidence they alter course disease.