Screening for lung cancer with low-dose spiral computed tomography.

摘要: Studies suggest that screening with spiral computed tomography can detect lung cancers at a smaller size and earlier stage than chest radiography can. To evaluate low-radiation-dose sputum cytology in for cancer, we enrolled 1,520 individuals aged 50 yr or older who had smoked 20 pack-years more prospective cohort study. One year after baseline scanning, 2,244 uncalcified nodules were identified 1,000 participants (66%). Twenty-five cases of cancer diagnosed (22 prevalence, 3 incidence). Computed alone detected 23 cases; 2 cases. Cell types were: squamous cell, 6; adenocarcinoma bronchioalveolar, 15; large 1; small 3. Twenty-two patients underwent curative surgical resection. Seven benign resected. The mean the non-small cell by was 17 mm (median, 13 mm). postsurgical IA, 13; IB, IIA, 5; IIB, IIIA, 2; limited, Twelve (57%) 21 IA diagnosis. early-stage cancers. rate nodule detection is high.