Estimation of exposure to atmospheric pollutants during pregnancy integrating space-time activity and indoor air levels: Does it make a difference?

摘要: Studies of air pollution effects during pregnancy generally only consider exposure in the outdoor at home address. We aimed to compare models differing their ability account for spatial resolution pollutants, space-time activity and indoor levels. recruited 40 pregnant women Grenoble urban area, France, who carried a Global Positioning System (GPS) up 3 weeks; subgroup, measurements fine particles (PM2.5) were conducted (n=9) personal nitrogen dioxide (NO2) was assessed using passive samplers (n=10). Outdoor concentrations NO2, PM2.5 estimated from dispersion model with resolution. Women spent on average 16 h per day home. Considering levels, estimates address, correlation between estimate nearest background monitoring station high (r=0.93) moderate (r=0.67) NO2. The incorporating clean GPS data less correlated relying raw (r=0.77) than ignoring (r=0.93). levels not moderately (r=-0.10 0.47), while NO2 (r=-0.42 0.03). In this accounting little influenced estimates; subgroup subjects (n=9), seemed strongly modify them.