作者: Max Greenfeld , Dmitri S. Pavlichin , Hideo Mabuchi , Daniel Herschlag
DOI: 10.1371/JOURNAL.PONE.0030024
关键词:
摘要: Single molecule studies have expanded rapidly over the past decade and ability to provide an unprecedented level of understanding biological systems. A common challenge upon introduction novel, data-rich approaches is management, processing, analysis complex data sets that are generated. We a standardized approach for analyzing these in freely available software package SMART: Molecule Analysis Research Tool. SMART provides format organizing easily accessing single data, general hidden Markov modeling algorithm fitting array possible models specified by user, structure graphical user interfaces streamline visualization data. This guides experimental design, facilitating acquisition maximal information from experiments. also allow dissemination transparency reported