Fecal Calprotectin May Predict Adverse Pregnancy-Related Outcomes in Patients with Inflammatory Bowel Disease.
作者： Parul Tandon , Eugenia Y. Lee , Cynthia Maxwell , Lara Hitz , Lindsy Ambrosio
DOI: 10.1007/S10620-020-06381-5
关键词:
摘要: Background The role of fecal calprotectin in predicting pregnancy-related outcomes inflammatory bowel disease (IBD) remains unknown. Aim To determine whether increased during pregnancy is associated with adverse IBD. Methods This a multicenter cohort study women IBD who underwent monitoring pregnancy. Fecal levels were stratified by trimester, and recorded. Mann-Whitney U test assessed differences between continuous variables, whereas categorical variables compared using the Chi-squared test. Results Eighty-five included. First trimester was higher patients emergency Cesarean birth to those had vaginal delivery (503 ug/g, IQR 1554.3 ug/g vs. 130 482 p = .030, respectively) delivered infants low weight normal (1511 579 168 413 .049, respectively). Third non-elective induction labor (334.5 1411.0 ug/g) spontaneous (116.5 227.1 (p .025). Those ≥ 250 second an incidence (35.3% 3.8%) .049), third (43.8% 10.3%, .030). Conclusions may be useful noninvasive marker predict
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