Mechanism of the silent period following transcranial magnetic stimulation. Evidence from epidural recordings.

作者: R. Chen , Andres M. Lozano , Peter Ashby

DOI: 10.1007/S002210050878

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摘要: We investigated the nature of silent period (SP) following transcranial magnetic stimulation by recording corticospinal volleys in a patient with implanted cervical epidural electrodes. Single suprathreshold test stimuli and paired at interstimulus intervals (ISIs) 50–200 ms were delivered while subject maintained constant background contraction. The duration from single stimulus was 357±62 ms. motor-evoked potentials markedly reduced all ISIs tested. I (indirect) waves induced largely unchanged an ISI 50 ms, suggesting that there little change motor cortex excitability. However, volleys, especially late waves, substantially 100 150 200 Our findings suggest early part SP is mainly due to spinal mechanisms, related

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