Regional Citrate Anticoagulation for Renal Replacement Therapy
作者： M. Balik , M. Zakharchenko , M. Matejovic
DOI: 10.1007/978-3-642-35109-9_58
关键词:
摘要: Compared to heparin, anticoagulation with citrate is associated almost no bleeding and superior circuit life enabling the delivery of high quality continuous renal replacement therapy (CRRT) [1–5]. The cumulative evidence indicating both efficacy safety regional has also been reflected in recent KDIGO (Kidney Disease: Improving Global Outcomes) guidelines suggesting use for prevention filter clotting preference standard even patients without an increased risk [6]. Moreover, advent semiautomated devices delivery, easy-to-learn operative protocols development commercially available calcium-free CRRT solutions, become favored modality many centers. Nevertheless, despite emerging data support potential superiority anticoagulation, several important issues remain unclear.
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