Improvement in Survival in TTP-HUS During the Past Decade: Prospective Study of 108 Patients

作者: W. Bell

DOI: 10.1007/978-3-642-80403-8_15

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摘要: Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, fever, central nervous system abnormalities, and renal dysfunction. In early reports the mortality approached 100%. A prospective treatment protocol was implemented on all patients admitted to Johns Hopkins Hospital (1979–1990) with diagnosis of TTP-HUS. Treatment regimens included.

参考文章(66)
James P. Crowley, Jaclyn B. Metzger, Ronald A. Leuropa, The blood counts and lactate dehydrogenase levels in thrombotic thrombocytopenic purpura (TTP). American Journal of Clinical Pathology. ,vol. 80, pp. 700- 702 ,(1983) , 10.1093/AJCP/80.5.700
Leo I. Gordon, Hau C. Kwaan, Ennio C. Rossi, Deleterious effects of platelet transfusions and recovery thrombocytosis in patients with thrombotic microangiopathy. Seminars in Hematology. ,vol. 24, pp. 194- 201 ,(1987)
C. Aul, R. E. Scharf, Th. Königshausen, W. Schneider, Thrombotisch-thrombozytopenische Purpura Journal of Molecular Medicine. ,vol. 63, pp. 123- 132 ,(1985) , 10.1007/BF01734250
Michal Rose, Amiram Eldor, High incidence of relapses in thrombotic thrombocytopenic purpura: Clinical Study of 38 Patients The American Journal of Medicine. ,vol. 83, pp. 437- 444 ,(1987) , 10.1016/0002-9343(87)90753-4
JA Katz, JL Moake, PD McPherson, MJ Weinstein, KJ Moise, RJ Carpenter, DJ Sala, Relationship between human development and disappearance of unusually large von Willebrand factor multimers from plasma. Blood. ,vol. 73, pp. 1851- 1858 ,(1989) , 10.1182/BLOOD.V73.7.1851.1851
Patricia M. Reynolds, John M. Jackson, John A.S. Brine, A.Brian Vivian, Thrombotic thrombocytopenic purpura—Remission following splenectomy The American Journal of Medicine. ,vol. 61, pp. 439- 447 ,(1976) , 10.1016/0002-9343(76)90385-5
Terry L. Evans, Alan Winkelstein, Zella R. Zeigler, Richard K. Shadduck, Kenneth F. Mangan, Thrombotic thrombocytopenic purpura: Clinical course and response to therapy in eight patients American Journal of Hematology. ,vol. 17, pp. 401- 407 ,(1984) , 10.1002/AJH.2830170410