Influence of heart rate on mortality among persons with hypertension: The Framingham Study

摘要: Abstract Previous studies have shown positive associations between heart rate and both all-cause cardiovascular mortality. These relationships, however, not been investigated in persons with hypertension. Using 36-year follow-up data from the Framingham Study, we evaluated 4530 subjects, aged 35 to 74, whose blood pressures were ≥140 mm Hg systolic or ≥90 diastolic who treated antihypertensive medication. We used pooled logistic regression calculate biennial mortality rates. Odds ratios 95% confidence intervals for each increment of 40 beats/min, adjusted age pressure level, were: , 2.18 (1.68, 2.83) men 2.14 (1.59, 2.88) women; 1.68 (1.19, 2.37) 1.70 (1.08, 2.67) women. Exclusion outcomes first 2 4 years after measurement did materially change results, which suggests that rapid is merely an indicator preexisting illness. Therefore may be independent risk factor death