作者: Ankit Saxena , S.K. Raychaudhuri , S.P. Raychaudhuri
DOI: 10.1016/B978-0-12-397803-5.00018-6
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摘要: Rheumatoid arthritis (RA) is a potentially destructive disease with profound impact on patients' function and quality of life. Newer therapeutic agents have revolutionized outcomes but not resulted in best for all patients. However, RA heterogeneous comprising several subsets patients variations pathogenesis. Elucidation these differences its molecular mechanisms may lead to better approaches. To treat more effectively, it essential intervene the earliest events pathophysiologic processes this disease. In chapter, we will present latest advances understanding process clinical relevance.