Staphylococcus aureus nasopharyngeal carriage in rural and urban northern Vietnam.

作者: Kinh Van Nguyen , Tianying Zhang , Bich Ngoc Thi Vu , Trinh Tuyet Dao , Toan Khanh Tran

DOI: 10.1093/TRSTMH/TRU132

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摘要: BACKGROUND Staphylococcus aureus is a common human pathogen that can colonise the respiratory tract and cause infection. Here we investigate risk factors associated with nasopharyngeal carriage of S. (including methicillin-resistant [MRSA]) in Vietnam. METHODS Between February June 2012, nasal pharyngeal swabs for culture, demographic socioeconomic data were taken from 1016 participants urban rural northern Vietnam, who randomly selected pre-specified age strata. RESULTS Overall prevalence was 303/1016 (29.8%; adjusted age: 33.8%). Carriage main cohort found to be younger (≤5 years [OR 3.13, CI 1.62-6.03]; 6-12 6.87, 3.95-11.94]; 13-19 6.47, 3.56-11.74]; 20-29 4.73, 2.40-9.31]; 30-59 1.74, 1.04-2.92); ≥60 as reference), living an area (OR 1.36, 1.01-1.83) antibiotics use 0.69, 0.49-0.96). MRSA detected 80/1016 (7.9%). Being aged ≤5 4.84, 1.47-15.97); 10.21, 3.54-29.50); 4.01, 1.09-14.77) wealth (>3/5 index, OR 1.63 1.01-2.62) significant carriage. CONCLUSIONS Nasopharyngeal present one-third Vietnamese population, more prevalent among children. Pharyngeal than Risk MRSA) are identified community.

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