Positron emission tomography to assess hypoxia and perfusion in lung cancer.

摘要: In lung cancer, tumor hypoxia is a characteristic feature, which associated with poor prognosis and resistance to both radiation therapy chemotherapy. As the development of decreased perfusion, perfusion measurements provide more insight into relation between in malignant tumors. Positron emission tomography (PET) highly sensitive nuclear imaging technique that suited for non-invasive vivo monitoring dynamic processes including its parameter perfusion. The PET enables quantitative assessment To this end, consecutive scans can be performed one scan session. Using different tracers, may prognostic significance cancer. addition, studies play an important role various stages personalized medicine, as these help select patients specific treatments therapy, modifying therapies, antiangiogenic strategies. tracers applied therapy. present review provides overview clinical applications measure Available their characteristics well combined are discussed.