Movement-Based Behaviors and Leukocyte Telomere Length among US Adults.
作者： PAUL D. LOPRINZI , JEREMY P. LOENNEKE , ELIZABETH H. BLACKBURN
DOI: 10.1249/MSS.0000000000000695
关键词:
摘要: AB Introduction: Short leukocyte telomere length (LTL) has become a hallmark characteristic of aging. Some, but not all, evidence suggests that physical activity (PA) may play an important role in attenuating age-related diseases and provide protective effect for telomeres. The purpose this study was to examine the association between PA LTL national sample US adults from National Health Nutrition Examination Survey. Methods: Survey data 1999 2002 (n = 6503; 20-84 yr) were used. Four self-report questions related movement-based behaviors (MBB) assessed. four MBB included whether individuals participated moderate-intensity PA, vigorous-intensity walking/cycling transportation, muscle-strengthening activities. An index variable created by summing number individual engaged (range, 0-4). Results: A clear dose-response relation observed LTL; across tertiles, respectively, mean numbers 1.18, 1.44, 1.54 (Ptrend < 0.001). After adjustments (including age) compared with those engaging 0 MBB, 1, 2, 3, 4 had 3% (P 0.84), 24% 0.02), 29% 0.04), 52% 0.004) reduced odds being lowest (vs highest) tertile associated middle LTL. Conclusions: Greater engagement
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