Elongated Nuclear Sheet and Intranuclear Myelin Figure of Human Medulloblastoma

摘要: Summary Nuclei of medulloblastoma cells revealed two types structural changes: formations cistern-limited nuclear sheets and intranuclear vacuolar profiles or myelin figures. The were extremely elongated contained on either side by the perinuclear cisterns. They usually composed a central granular beaded heterochromatin layer between less dense layers, further limited inner membrane, showed an approximately constant width 350 430 A. in sheet was continuous with peripheral granules nuclei. In addition, periphery seen membrane layer. association its underlying layer, as well similar seemed to form functional unit. vaculoar figures irregular might be derived from membranes complicated, invagination. demonstrated increased density thickness surrounded flocculent substances islands cytoplasm not covered layers.