Central inhibition of refractory overactive bladder complaints, results of an inpatient training program.

作者: E.F.J. Meijer , A.J. Nieuwhof-Leppink , E. Dekker-Vasse , G.C.J. de Joode-Smink , T.P.V.M. de Jong

DOI: 10.1016/J.JPUROL.2014.06.024

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摘要: Summary Short introduction Overactive bladder (OAB) in children has an overall reported incidence of 16.6–17.8%, with its prevalence 0.2–9% varying largely between age and gender. OAB is the most important burden pediatric urology because limited effect treatment. imperative urge and/or incontinence can often be successfully treated urotherapy pharmacological Nevertheless, approximately 20% patients are considered to therapy resistant for common treatment options. For latter group, inpatient cognitive biofeedback training program been developed. Objective Our objective evaluate complaints based on overactive after failed earlier by anticholinergic medication outpatient urotherapy. A search predictors success outcome included study. Study design Seventy refractory went through a 10-day in-hospital 2007 2010. The were aged 7 13 years (mean 9.29 years) 48 (68.6%) male. An essential part this teaching central inhibition their suppress overactivity. Before attending had average 41.1 months fruitless medication, if needed preceding surgery meatus correction or deobstruction. result was evaluated 6 completion program. questionnaire subsequently conducted 2 long-term efficacy Results Six training, evaluation showed that 30 70 (42.9%) free complaints, 22 (31.4%) significant reduction 18 (25.7%) no improvement. Logistic regression analysis used look at several variables predicting outcome. higher during clinical found predictor good After years, 44 (62.9%) reached follow-up. Of these patients, 28 (63.6%) 11 (25%) experienced improvement symptoms compared before training. Objectively, 26 (59.1%) dry (40.9%) incontinent some extent. total (68.2%) not relapsed into (McNemar’s test P -value Table. . results, n = 70, mean 9.3 (SD 1.46, Min Max years). Variables Result Frequency Percent (100%) short-term Bad 18/70 25.7 n/a Improvement 22/70 31.4 Good 30/70 42.9 Multiple Higher 0.034 11/44 25 5/44 11.4 28/44 63.6 Urge Yes 14/44 31.8 b No 30/44 68.2 Using logistic analysis. McNemar’s test. Discussion Age result, which line findings other publications where above 8 demonstrate better faster results. absolute number participants perform statistical low, even though it maximally achievable cohort, possibly explaining how could predict differences results observed having received our hospital when being trained elsewhere. This coherent previous research indicating attention offered child paramount importance. Regarding follow-up, keeping mind follow-up patient numbers incomplete, seen clear complaints. Far fewer suffering from although Conclusion demonstrated cure improve 74.3% conveyed favorable 75.0% patients.

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