Functional Mapping of Learning-Related Metabolic Activity with Quantitative Cytochrome Oxidase Histochemistry

摘要: Utilizing quantitative histochemistry to view increases or decreases in the activity of mitochondrial enzyme cytochrome oxidase (C.O.) affords a new functional neuroimaging technique for examining baseline changes which have taken place over period time, as opposed evoked alone. Cytochrome is pivotal oxidative energy production cells. The amount this tightly coupled aerobic metabolism This chapter will describe how recent advances histochemical quantification enzymatic been used look at even relatively small resulting from learning experiences map circuitry associative learning. All three studies described here demonstrate acoustic stimuli can modify auditory system and create distinct patterns metabolic when stimulus acquires different behavioral roles through mapping provide images capacity intact neural systems change response external stimuli.