Frequency of biocide resistance genes, antibiotic resistance and the effect of chlorhexidine exposure on clinical methicillin-resistant Staphylococcus aureus isolates
作者： L. Vali , S. E. Davies , L. L. G. Lai , J. Dave , S. G. B. Amyes
DOI: 10.1093/JAC/DKM520
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摘要: Results: qacA/B (8.3%), qacH (3.3%), norA (36.7%), smr (44.2%) and blaZ (97.5%) were prevalent within the population but qacG was not detected. EMRSA-15 (19.2%), EMRSA-16 (15%), P3 (15%) H (12.5%) most common PFGE types. Clinical isolates demonstrated various degrees of susceptibility to chlorhexidine in surface disinfection [mean microbiocidal effect (ME) 5 0‐1.91] biocide residue (mean ME 0.29‐3.74) tests. Increases post-exposure MICs observed both susceptible S. aureus control. Conclusions: In our study, resembling type harboured more resistance genes than other The reduction clinical may mean that a selective pressure is being exerted by residues environment, highlights importance efficacy testing on strains good infection control practices. development reduced microbial biocides represents serious cause for concern environment.
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