Reduced proportion of decidual DC-SIGN+ cells in human spontaneous abortion
作者： I Tirado-González , R Muñoz-Fernández , O Blanco , E Leno-Durán , AC Abadía-Molina
DOI: 10.1016/J.PLACENTA.2010.09.008
关键词:
摘要: Recent studies showed that some functions of decidual dendritic cells appear to be essential for pregnancy. In humans, are identifiable by their expression DC-SIGN. We compared the subpopulations human DC-SIGN+ from first-trimester normal pregnancies and spontaneous abortions flow cytometry. decidua, expressed antigens associated with immature myeloid cells. samples abortions, we detected an antigen phenotype equivalent pregnancies, but at a significantly lower proportion (P < 0.01). Our results support hypothesis play role in or pathological pregnancy outcomes.
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sci-hub.se 参考文章(22)
Muriel Moser, Kenneth M. Murphy, Dendritic cell regulation of TH1-TH2 development. Nature Immunology. ,vol. 1, pp. 199- 205 ,(2000) , 10.1038/79734
Gordana Laskarin, Ulrike Kämmerer, Daniel Rukavina, Angus W Thomson, Nelson Fernandez, Sandra M Blois, Antigen-presenting cells and materno-fetal tolerance: an emerging role for dendritic cells. American Journal of Reproductive Immunology. ,vol. 58, pp. 255- 267 ,(2007) , 10.1111/J.1600-0897.2007.00511.X
Enrique G Olivares, Raquel Munoz, German Tejerizo, Maria Jose Montes, Francisca Gómez-Molina, Ana Clara Abadía-Molina, None, Decidual Lymphocytes of Human Spontaneous Abortions Induce Apoptosis but Not Necrosis in JEG-3 Extravillous Trophoblast Cells Biology of Reproduction. ,vol. 67, pp. 1211- 1217 ,(2002) , 10.1095/BIOLREPROD67.4.1211
Elizabeth J. Soilleux, Lesley S. Morris, Benhur Lee, Stefan Pöhlmann, John Trowsdale, Robert W. Doms, Nicholas Coleman, Placental expression of DC-SIGN may mediate intrauterine vertical transmission of HIV The Journal of Pathology. ,vol. 195, pp. 586- 592 ,(2001) , 10.1002/PATH.1026
Ulrike Kämmerer, Michael Schoppet, Alexander D. McLellan, Michaela Kapp, Hans-Iko Huppertz, Eckhart Kämpgen, Johannes Dietl, Human decidua contains potent immunostimulatory CD83(+) dendritic cells. American Journal of Pathology. ,vol. 157, pp. 159- 169 ,(2000) , 10.1016/S0002-9440(10)64527-0
MICHAEL PLEVYAK, NAZEEH HANNA, SANDRA MAYER, SHAUN MURPHY, HALIT PINAR, LOREN FAST, CHRISTINA EKERFELT, JAN ERNERUDH, GORAN BERG, LEIF MATTHIESEN, SURENDRA SHARMA, Deficiency of decidual IL-10 in first trimester missed abortion: a lack of correlation with the decidual immune cell profile. American Journal of Reproductive Immunology. ,vol. 47, pp. 242- 250 ,(2002) , 10.1034/J.1600-0897.2002.01060.X
M. MARZI, A. VIGANO, D. TRABATTONI, M. L. VILLA, A. SALVAGGIO, E. CLERICI, M. CLERICI, Characterization of type 1 and type 2 cytokine production profile in physiologic and pathologic human pregnancy. Clinical and Experimental Immunology. ,vol. 106, pp. 127- 133 ,(1996) , 10.1046/J.1365-2249.1996.D01-809.X
Sandra M. Blois, Catalina D. Alba Soto, Mareike Tometten, Burghard F. Klapp, Ricardo A. Margni, Petra C. Arck, Lineage, Maturity, and Phenotype of Uterine Murine Dendritic Cells Throughout Gestation Indicate a Protective Role in Maintaining Pregnancy Biology of Reproduction. ,vol. 70, pp. 1018- 1023 ,(2004) , 10.1095/BIOLREPROD.103.022640
Jean Claude Gluckman, Francoise Sanchez-Chapuis, Nicolas Taquet, Karolina A. Palucka, Dendritic Cells as the Terminal Stage of Monocyte Differentiation Journal of Immunology. ,vol. 160, pp. 4587- 4595 ,(1998)
Marie-Clotilde Rissoan, Vassili Soumelis, Norimitsu Kadowaki, Geraldine Grouard, Francine Briere, René de Waal Malefyt, Yong-Jun Liu, Reciprocal Control of T Helper Cell and Dendritic Cell Differentiation Science. ,vol. 283, pp. 1183- 1186 ,(1999) , 10.1126/SCIENCE.283.5405.1183