Adjustable chiral self-sorting and self-discriminating behaviour between diamond-like Tröger's base-linked cryptands

摘要: Two isomers of Troger's base-linked cryptands 5a and 5b were synthesized, both them have two chiral N-centers, exhibiting rare diamond-like scaffolds. Particularly, when growing from the solution rac-5a, a single enantiomer RNRN-5a was found in crystal cell, revealing self-sorting behaviour. However, adding CF3COOH to protonate base enantiomers formed pairs self-discriminating