Histoplasma capsulatum at the host–pathogen interface

摘要: Histoplasma capsulatum is the most common cause of invasive fungal pulmonary disease worldwide. The interaction H. with a host complex, dynamic process. Severe commonly occurs in individuals compromised immunity, and increasing utilization immunomodulators medicine has revealed significant risks for reactivation patients latent histoplasmosis. Fortunately, there are well developed molecular tools excellent animal models studying virulence numerous recent advances have been made regarding pathogenesis this fungus that will improve our capacity to combat disease.