Collagen synthesis in human musculoskeletal tissues and skin
作者： J. A. Babraj , D. J. R. Cuthbertson , K. Smith , H. Langberg , B. Miller
DOI: 10.1152/AJPENDO.00243.2005
关键词:
摘要: We have developed a direct method for the measurement of human musculoskeletal collagen synthesis on the basis of the incorporation of stable isotope-labeled proline or leucine into protein and have used it to measure the rate of synthesis of collagen in tendon, ligament, muscle, and skin. In postabsorptive, healthy young men (28±6 yr) synthetic rates for tendon, ligament, muscle, and skin collagen were 0.046±0.005, 0.040±0.006, 0.016±0.002, and 0.037±0.003%/h, respectively (means±SD). In postabsorptive, healthy …
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