Homogenous, far-reaching tuning and highly emissive QD–silica core–shell nanocomposite synthesized via a delay photoactive procedure; their applications in two-photon imaging of human mesenchymal stem cells
作者： Chih-Wei Lai , Yu-Hsiu Wang , Yu-Chun Chen , Cheng-Chih Hsieh , Borade Prajakta Uttam
DOI: 10.1039/B906575J
关键词:
摘要: In this article, we present the exploration of a facile synthetic tactic incorporating delay-photo-oxidation to recover loss in emission frequently encountered after encapsulating quantum dots (QDs) inside silica shell. This synthesis procedure reproducibly increases emissive intensity QDs (core)–SiO2 (shell) (60 nm) nanomaterials by >5 fold (QY from 3% >15%). The resulting proved be single dot SiO2, homogeneous and highly monodispered; their emissions have been successfully fine-tuned visible near infrared region. We then demonstrate power biological imaging labeling human mesenchymal stem cells under two-photon confocal microscopy. results low cytotoxicity, efficient labeling, specific location nearby nucleus characters these nanoparticles should spark an intensive relevant research within living system.
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