Injectable Nanohybrid Scaffold for Biopharmaceuticals Delivery and Soft Tissue Engineering
作者： Huaping Tan , Qing Shen , Xiaojia Jia , Zipeng Yuan , Dangsheng Xiong
关键词:
摘要: An injectable nanofibrous hydrogel scaffold integrated with growth factors (GFs) loaded polysaccharide nanoparticles was developed that specifically allows for targeted adipose-derived stem cells (ASCs) encapsulation and soft tissue engineering. The produced via biological conjugation of biotin-terminated star-shaped poly(ethylene glycol) (PEG-Biotin) streptavidin-functionalized hyaluronic acid (HA-Streptavidin). were noncovalently assembled electrostatic interactions between low-molecular-weight heparin (LMWH) N,N,N-trimethylchitosan chloride (TMC). Vascular endothelial factor (VEGF) entrapped in the LMWH/TMC by affinity LMWH.
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