The distribution of antibiotic resistance genes in chicken gut microbiota commensals
作者： Jitka Matiasovicova , Helena Juricova , Ivan Rychlik , Tereza Kubasova , Darina Cejkova
DOI: 10.1038/S41598-021-82640-3
关键词:
摘要: Antibiotic resistance in bacterial pathogens or several indicator bacteria is commonly studied but the extent of antibiotic commensals colonising intestinal tract essentially unknown. In this study, we aimed to investigate presence horizontally acquired genes among chicken gut microbiota members 259 isolates with known whole genomic sequences. Altogether 124 contained at least one gene coding for resistance. Genes tetracyclines (detected 101 isolates), macrolide-lincosamide-streptogramin B antibiotics (28 isolates) and aminoglycosides (25 were most common. The frequent tetracycline tet(W), tet(32), tet(O) tet(Q). Lachnospiraceae Ruminococcaceae frequently encoded tet(W). coded also tet(32) tet(O). tet(44) was associated Erysipelotrichaceae tet(Q) detected genomes Bacteroidaceae Porphyromonadaceae. Without any bias have shown that quite common commensals. However, a comparison codon usage showed above-mentioned families represent current reservoirs probably not original host resistances.
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