Efficient generation of an oxidopyrylium ylide using a Pd catalyst and its [5+2] cycloadditions with several dipolarophiles.
作者： Hiroyuki Suga , Taichi Iwai , Masahiro Shimizu , Kie Takahashi , Yasunori Toda
DOI: 10.1039/C7CC09552J
关键词:
摘要: An efficient method for the generation of an oxidopyrylium ylide from 6-acetoxy-6-acetoxymethyl-2H-pyran-3(6H)-one using a Pd catalyst and [5+2] cycloadditions resulting are described. Among substituted styrene derivatives as dipolarophiles, electron-rich styrenes showed higher yield (up to 80%). The cycloaddition reactions can also be applied exo-methylene cyclic compounds, improved synthesis polygalolide intermediate has been demonstrated.
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