作者: Meletios A. Dimopoulos , Jesus F. San-Miguel , Kenneth C. Anderson
DOI: 10.1111/J.1600-0609.2010.01542.X
关键词:
摘要: Encouraging progress has been made in the treatment of patients with relapsed/refractory multiple myeloma (MM). The rapidly evolving understanding key pathways responsible for tumor growth and survival led to development novel agents (including immunomodulatory drugs, proteasome inhibitors, histone deacetylase other targeted agents) potential provide significant improvements response survival, influence guidelines. This review summarizes recent advances biology MM clinical trials that are currently under investigation this disease.