Spontaneous remission of epstein-barr virus-positive diffuse large B-cell lymphoma of the elderly.

摘要: A 94-year-old female patient presented with anorexia and left axillar lymphadenopathy on admission. Her past history was angina pectoris at 83 years of age total gastrectomy due to gastric cancer 87 years. The family revealed that her son had a malignant lymphoma, the histopathological diagnosis which diffuse large B-cell lymphoma. physical examination showed both cervical, axillar, inguinal without tenderness. She elevated lactate dehydrogenase, ferritin, soluble interleukin-2 receptor (sIL-2R). Whole-body computed tomography confirmed axillary, lymphadenopathy. Gallium-68 imaging positive accumulation in these superficial lymph nodes. right node biopsy features Epstein-Barr virus-associated lymphoproliferative disorder. Immunohistological studies this CD20-positive cells, CD3-positive small CD30-partly-positive cells. In situ hybridization virus-positive, LMP-partly-positive, EBNA2-negative refused chemotherapy as died from hematemesis during chemotherapy. received intravenous hyperalimentation for 1 month after No palpable nodes were identified by or 3 months admission, regression sIL-2R observed. recovered discharged. pneumonia 10 later initial symptoms anorexia. autopsy no