Long-term Follow-up of Intraductal Papillary Mucinous Neoplasm of the Pancreas With Ultrasonography

摘要: Background & Aims: Most intraductal papillary mucinous neoplasms of the pancreas (IPMNs) have a favorable prognosis. This study was undertaken to clarify clinical course IPMNs and set criteria for surgical treatment on basis long-term follow-up by periodic transabdominal ultrasonography (US). Methods: Eighty-one patients with IPMN were periodically subjected US (>3 years); 27 reviewed retrospectively (12 benign [adenoma, borderline] 15 malignant tumors [carcinoma in situ, invasive cancer]) 54 prospectively. examination focused main pancreatic duct (MPD) diameter, cyst presence or absence height protruding lesion. Differences between groups examined treatment. Follow-up results prospective investigated. Results: The increase MPD diameter significantly greater group (P < .01). Maximum increases 2.2 mm/year, 11.3 emergence lesion 3.3 mm/year predominantly observed (accuracy, 90.9%, 81.3%, 81.5%, respectively). majority showed no significant changes these parameters; however, 2 (3.7%) operated on, post-surgery histopathologic diagnosis cancer. Conclusions: Periodic imaging is useful detect IPMN. Changes and/or size are practical selecting surgery.