THE FATTY-ACID COMPOSITION OF PHOSPHATIDYLINOSITOL, PHOSPHATIDATE AND 1,2-DIACYLGLYCEROL IN STIMULATED HUMAN-NEUTROPHILS

摘要: The fatty acid composition of phosphatidylinositol (PtdIns), phosphatidate (PtdOH) and 1,2-diacylglycerol (DG) was determined in cytochalasin B-treated human neutrophils the presence absence formylmethionyl-leucyl-phenylalanine. compositions PtdOH DG stimulated cells resemble closely that control are quite different from PtdIns. appears to be produced as a subsequent metabolite not an intermediate conversion PtdIns into PtdOH. We conclude is directly small pool newly synthesized neutrophils.