Is Distraction Osteogenesis of the Irradiated Craniofacial Skeleton Contraindicated

摘要: Background Craniofacial distraction osteogenesis (DO) is a common treatment modality today. Despite its numerous advantages, however, concerns have been expressed regarding the use of DO in irradiated setting. Methods A systematic review was performed to identify all published reports patients who underwent craniofacial skeleton. The following parameters were particular interest: postoperative complications, specifically, insufficient bone formation, fracture, and hardware exposure (intraoral cutaneous), as well need for additional grafting. Results initial search retrieved total 183 articles which 20 (38 patients) met predetermined inclusion criteria. most site mandible (76.3%). median radiation dose 50.7 Gy (range, 30-70 Gy). Bone defects ranged from 30 80 mm (median, 42.5 mm). Complications encountered 19 (50%), with formation being (9 patients; 23%). overall incidence complications not significantly associated dosage (P = 0.79). remaining procedural demographic variables also failed meet statistical significance when compared against complication rate 0.27-0.97). Conclusion skeleton does appear be substantially higher than what reported nonirradiated As such, should offered this modality, particularly light fact, that it offers option decrease patient morbidity complexity.