SRPKIN-1: A Covalent SRPK1/2 Inhibitor that Potently Converts VEGF from Pro-angiogenic to Anti-angiogenic Isoform

作者: John M. Hatcher , Guowei Wu , Chuyue Zeng , Jie Zhu , Fan Meng

DOI: 10.1016/J.CHEMBIOL.2018.01.013

关键词:

摘要: The SRPK family of kinases regulates pre-mRNA splicing by phosphorylating serine/arginine (SR)-rich splicing factors, signals splicing control in response to extracellular stimuli, and …

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