Health-related quality of life and its determinants among ambulatory patients with epilepsy at Ambo General Hospital, Ethiopia: Using WHOQOL-BREF.

摘要: BACKGROUND Health-related quality of life (HRQOL) is used as a measure treatment outcomes, in addition to seizure control. Hence, the study was aimed assess HRQOL and its determinants among adult patients with epilepsy (PWE). METHOD A hospital-based cross-sectional conducted from April 20 June 27/2019, through patient interviews patient's chart review (medication clinical information). Data were analyzed using SPSS version 20. The psychometric property done Cronbach's alpha test value >0.7 accepted internal consistency Kaiser-Meyer-Olkin (KMO) sample size adequacy ≥0.5 acceptable construct validity, for Afaan Oromo questionnaire. Multivariate linear logistic regression analysis find predictors score. RESULTS Of 121 PWE included study, 24.4% had overall poor mean ±SD score 56.42±10.96. low were: presence co-morbidity (B = -5.620, SE 1.531, p<0.0001, 95% C.I -8.656 -2.584), uncontrolled at least 2 years -4.239, 1.296, p 0.001, -6.809 -1.670), divorced -8.423, 2.241, 95%C.I -12.867 -3.978) relative married, no education -8.715, -8.15, 2.604, -9.648 -1.316) who level above tertiary. In addition, (irrespective time since seizure-free) -10.083, 2.104, -14.256 -5.910), being widowed -9.300, 3.594, 0.011, -16.429-2.170) married illiterate/no -13.004, 3.910, -20.760 -5.248) educational tertiary found be strongest negative physical health. Moreover, -12.668, 2.019, -16.671 -8.664) -10.153, 3.228, 0.002, -16.556 -3.751) compared strong psychological Absence Poly-pharmacy 9.050, 3.027, P 0.003, 3.047 15.054), single -9.551, 2.095, -14.419 -4.683), -11.022, 3.351, -17.668 -4.376) social environmental health predicted by rural residence -5.795, 2.101, 0.007, -9.962 -1.628), (B+ -4.230, 2.125, 0.049, -8.444 -0.015) & irrespective seizure-free -6.907, 1.945, -10.765 -3.049) -4.520, 1.798, 0.014, -8.088 -0.953). CONCLUSIONS majority participants good HRQOL. general, significantly associated marital status single/widowed/divorced, education, monthly income, co-morbidity, seizure, poly-pharmacy; domains. Therefore, it required improve HRQOL, avoiding modifiable factors achieve optimum