Installation and use of LabKey Server for proteomics.
作者： Joshua Eckels , Peter Hussey , Elizabeth K. Nelson , Tamra Myers , Adam Rauch
DOI: 10.1002/0471250953.BI1305S36
关键词:
摘要: LabKey Server (formerly CPAS, the Computational Proteomics Analysis System) provides a Web-based platform for mining data from liquid chromatography–tandem mass spectrometry (LC-MS/MS) proteomic experiments. This open source supports systematic analyses and secure management, integration, sharing. incorporates several tools currently used in analysis, including X! Tandem search engine, ProteoWizard toolkit, PeptideProphet ProteinProphet tools. These others are integrated into Server, which an extensible architecture developing high-throughput biological applications. The analysis pipeline acts on standardized file formats, so that researchers may use with other engines, Mascot or SEQUEST, follow format reporting engine results. Supported builds of freely available at http://www.labkey.com/. Documentation code under Apache License 2.0 http://www.labkey.org. Curr. Protoc. Bioinform. 36:13.5.1-13.5.25. © 2011 by John Wiley & Sons, Inc. Keywords: liquid chromatography; mass spectrometry; proteomics; data analysis; protein identification
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