Disparities in knowledge and willingness to donate research biospecimens: a mixed-methods study in an underserved urban community

摘要: Although research involving biospecimens is essential in advancing cancer research, minorities, especially African-Americans, are underrepresented such research. We conducted a mixed-method (qualitative focus groups among African-Americans and quantitative cross-sectional surveys) study on factors associated with biospecimen knowledge donation intent the medically underserved urban communities Southeast Southwest Washington, DC. Focus were 41 survey data was available from 302 community residents of different races/ethnicities using convenience sampling. used logistic regression to model association between selected sociodemographic variables data. Only 47 % participants had types biospecimens. In multivariate models, male gender, African-American race, low education levels significantly lower about Compared Whites (79 %), fewer (39 %) Hispanics (57 but difference significant for only. Positive donate observed 36 respondents. After adjustment, only (odds ratio = 1.91, 95 confidence interval 1.12, 3.27). Contrary popular opinion, “mistrust medical community” not most commonly reported barrier African-Americans. “Not knowing how will be used” “lack biospecimens” common barriers. Our highlights importance increase minority participation