Double Pore Silica Gel Monolith Applied to Liquid Chromatography

摘要: Silica gels retaining double pore structure in the size ranges of micrometer and nanometer have been applied to rod-shaped monolithic column for liquid chromatography. The macropore was designed by controlling phase separation process induced hydrolysis polycondensation alkoxysilane, whereas mesopore tailored solvent exchange treatments on wet gels. exclusion chromatograms polystyrene standards exhibited almost similar features octadecyl-modified rod conventional packed beads columns. dependence plate height velocity mobile determined amylbenzene far weaker than column, suggesting that additional geometrical factors should be considered describing mechanism column.