Algorithms for pharmacological treatment of personality dimensions: symptom-specific treatments for cognitive-perceptual, affective, and impulsive-behavioral dysregulation.

摘要: A pharmacological approach to treating patients with personality disorders (PD) is based on evidence that some dimensions of are mediated by variations in neurotransmitter physiology and responsive medication effects. Target symptoms for pharmacotherapy the PD patient derived from expressions cognitive-perceptual, affective, impulsive-behavioral dysregulation central functions. Pharmacotherapy directed at state during periods acute decompensation trait vulnerabilities, which represent diathesis future episodes. basic assumption this biology transcends Axis I II definitions closely related may share a common pathophysiology, independent categorical definition. pathophysiology implies possibility shared responsiveness medication. Using dimensional definition symptom domains, author has developed treatment algorithms cognitive-perceptual symptoms, affective dysregulation, dyscontrol disorder patients.