An epidemic spread of multiresistant Pseudomonas aeruginosa in a cystic fibrosis centre

摘要: Early in 1983 an epidemic of a Pseudomonas aeruginosa resistant to aminoglycosides, carbenicillin, ureidopenicillins, ceftazidime, cefsulodin and imipenem occurred cystic fibrosis centre. Most the could be attributed specific nosocomial strain by means O-grouping phage-typing. This was present centre at low frequency 1973 developed resistance during courses chemotherapy. The stopped isolating patients with strains. Restrictive selective use antibiotics have not been sufficient eradicate strains, which persist 42% patients. extensive third generation cephalosporins clinic is probably responsible for inducing selecting Clustering has facilitated spread. First-line older beta-lactam antibiotics, close bacteriological monitoring prompt isolation strains are recommended.